民 族

汉族

籍 贯

山东临沂

最高学位

博士

职称/职务

副教授

社会兼职

联系方式

邮箱：wangchao@sust.edu.cn

实验楼1A-405（应化教研室）/实训楼4002实验室

学习及工作经历

2017.03-现在 陕西科技大学  化学与化工学院   副教授   硕士生导师

2012.09-2017.01 大连理工大学  应用化学专业   博士

2009.09-2012.06 华东理工大学  有机化学专业   硕士

2005.09-2009.06 烟台大学  应用化学专业  本科

主要研究方向

(1)        荧光探针的合成与生物分析应用

(2)        细胞蛋白质特异性荧光标记与成像

承担

的主

要项

目及

成果

作为负责人承担项目：

（1）国家自然科学基金青年项目，21708023，蛋白靶向的比率型谷胱甘肽荧光探针构建与亚细胞定量检测研究

（2）中国博士后面上二等资助西部计划项目，2019M653850XB，可逆型谷胱肽荧光探针的细胞器靶向设计与检测研究

（3）陕西省自然科学基础研究计划青年项目，2019JQ-061，基于聚集诱导发光分子的蛋白质特异性标记策略设计与生物应用研究

（4）陕西科技大学博士科研启动金，2017GBJ-04，亚细胞蛋白特异性荧光标记与生物分析应用研究

发表学术论文：

[1] Wang Chao*, Wang   Tingting, Zhao Min, Dai Fangfang, Niu Zhuolan, Zhang Wenqing, Ma Yangmin*.   A simple chalcone molecular rotor for specific fluorescence imaging of   mitochondrial viscosity changes in living cells. Dyes and Pigments,   2021, 194: 109593.（SCI一区）

[2] Wang Chao, Jia Minjie, Bai Zhe, Shi   Midong, Chen Xiangli, Fan Juan, Dai Fangfang*. The   separation of isopropyl alcohol from diisopropyl ether system using glycols:   Phase equilibrium and rigorous correlation. Journal of Chemical   Thermodynamics, 2020, 150.（SCI三区）

[3] Dai Fangfang, Zhao Min, Yang Fangzhou,   Wang Tingting, Wang Chao*. An ESIPT coupled AIE fluorescent probe for   biothiols detection and imaging based on a chalcone fluorophore. Dyes   and Pigments, 2020, 183: 108627.（SCI一区）

[4] Zhang Xinfu, Wang Benlei, Xiao Yi*,   Wang Chao, He Ling. Targetable, two-photon fluorescent probes for   local nitric oxide capture in the plasma membranes of live cells and brain   tissues. Analyst, 2018, 143(17): 4180-4188.（SCI二区）

[5] Huang Zhenlong, Li Ning, Zhang Xinfu, Wang   Chao, Xiao Yi*. Fixable Molecular Thermometer for Real-Time   Visualization and Quantification of Mitochondrial Temperature. Analytical   Chemistry, 2018, 90(23): 13953-13959.（SCI一区）

[6] Yang Fu¹, Wang   Chao¹, Wang Lu, Ye Zhi-Wei, Song Xin-Bo, Xiao Yi*.   Hoechst-naphthalimide dyad with dual emissions as specific and ratiometric   sensor for nucleus DNA damage. Chinese Chemical Letters, 2017,   28(10): 2019-2022.（SCI二区）

[7] Wang Chao¹, Song Xinbo¹, Xiao   Yi. SNAP-Tag-based subcellular protein labeling and fluorescent imaging with   naphthalimides. ChemBioChem, 2017, 18(17): 1762-1769.（SCI三区）

[8] Wang Chao, Song Xinbo, Chen   Lingcheng, Xiao Yi*. Specifically and wash-free labeling of   SNAP-tag fused proteins with a hybrid sensor to monitor local   micro-viscosity. Biosensors & Bioelectronics, 2017, 91:   313-320.（SCI一区）

[9] Song Xinbo, Bian Hui, Wang Chao, Hu   Mingyu, Li Ning, Xiao Yi*. Development and applications of a   near-infrared dye-benzylguanine conjugate to specifically label SNAP-tagged   proteins. Organic & Biomolecular Chemistry, 2017, 15:   8091-8101.（SCI三区）

[10] Wang Chao¹, Song Xinbo¹, Han   Zhuo, Li Xiaoyu, Xu Yongping, Xiao Yi*. Monitoring   Nitric Oxide in Subcellular Compartments by Hybrid Probe Based on Rhodamine   Spirolactam and SNAP-tag. ACS Chemical Biology, 2016, 11: 2033-2040.（SCI二区）

[11] Zhang Xinfu, Wang Benlei, Wang Chao,   Chen Lingcheng, Xiao Yi*. Monitoring Lipid Peroxidation within Foam   Cells by Lysosome-Targetable and Ratiometric Probe. Analytical Chemistry,   2015, 87(16): 8292-8300.（SCI一区）

[12] Wang Jianhua¹, Zhao Yuzheng¹, Wang Chao¹, Zhu Qian, Du Zengmin, Hu Aiguo*, Yang Yi*. Organelle-Specific Nitric Oxide Detection in   Living Cells via HaloTag Protein Labeling. PLoS One, 2015,   10(4): e0123986.（SCI三区）

[13] Song Xinbo¹, Wang   Chao¹, Han Zhuo, Xu Yongping, Xiao Yi*.   Terminal alkyne substituted O⁶-benzylguanine for versatile and   effective syntheses of fluorescent labels to genetically encoded SNAP-tags. RSC   Advances, 2015, 5(30): 23646-23649.（SCI三区）